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Publications

Thesis: Robot-Trifle: A Robotic System for Automated Combinatorial Growth Phenotyping

A master’s thesis from Jeremy Kimball at the University of Illinois describing a streamlined, automated analysis pipeline to…
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Publications

Measuring Luteinising Hormone Pulsatility with a Robotic Aptamer-Enabled Electrochemical Reader

Normal reproductive functioning is critically dependent on pulsatile secretion of luteinising hormone (LH). Assessment of LH pulsatility is important for…
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Publications

Fully Automated Sample Processing and Analysis Workflow for Low-Input Proteome Profiling

Recent advances in sample preparation and analysis have enabled direct profiling of protein expression in single mammalian cells and other…
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A Semiautomated Paramagnetic Bead-Based Platform For Isobaric Tag Sample Preparation

The development of streamlined and high-throughput sample processing workflows is important for capitalizing on emerging advances and innovations in mass…
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Publications

FusX: A Rapid One-Step Transcription Activator-Like Effector Assembly System for Genome Science

Transcription activator-like effectors (TALEs) are extremely effective, single-molecule DNA-targeting molecular cursors used for locus-specific genome science applications, including high-precision molecular…
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PlasmoTron: an Open-Source Platform For Automated Culture of Malaria Parasites

We have created a system which allows an inexpensive opensource liquid-handling robot to automate most aspects of bloodstage malaria parasite…
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Publications

Synthetic Genetic Codes Designed to Hinder Evolution

One challenge in engineering organisms is guaranteeing system behavior over many generations. Spontaneous mutations that arise before or during use…
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Drag-and-drop Genome Insertion without DNA Cleavage with CRISPR-Directed Integrases

Programmable and multiplexed genome integration of large, diverse DNA cargo independent of DNA repair remains an unsolved challenge of genome…
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Publications

Rapid Production and Recovery of Cell Spheroids by Automated Droplet Microfluidics

The future of the life sciences is linked to automation and microfluidics. As robots start working side by side with…
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Publications

Improving Reproducibility in Synthetic Biology

Synthetic biology holds great promise to deliver transformative technologies to the world in the coming years. However, several challenges still…
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